ENGLEWOOD, Colo. — There are seven quarterbacks in the NFL who have rushed for at least 100 yards this season.

And by the time Sunday night’s game is over for the Denver Broncos, the team’s defense will have faced four of them. The Broncos have already chased Seattle’s Russell Wilson (221 yards rushing), Kansas City’s Alex Smith (108 yards rushing) and the Jets’ Geno Smith (102 yards).

And in prime time this weekend they get the rushing leader at the position in the San Francisco 49ersColin Kaepernick. Kaepernick leads all of the league’s quarterbacks with his 242 yards rushing and is coming off a game when he also threw for 343 yards against the St. Louis Rams on Monday.

“The way he runs the ball, he’s not running to get first downs, he’s running to score,” said Broncos quarterback Peyton Manning.

Manning doesn’t often study the opposing quarterback in a game week, he’s got his own issues to contend with, but Kaepernick is different. Kaepernick was a counselor at the Manning Passing Academy before Kaepernick’s final season at the University of Nevada.

“I can remember having some conversations with Colin,” Manning said. “I could tell he was a very intense guy that was very eager to learn and what a great start to his career. It’s been fun to follow those guys that have been down there.”

For the most part the Broncos have contained the running passers they have faced — holding Alex Smith to 42 yards rushing and Geno Smith to 11 yards. The Broncos were also disciplined in their approach for much of a Week 3 loss against the Seahawks as they contained Wilson in regulation.

But Wilson got loose in overtime, rushing for 21 of his 40 yards in the game on Seattle’s game-winning …read more